Demethylating agent 5-aza-2'-deoxycytidine activates HLA-G expression in human leukemia cell lines.

@article{Polkov2009DemethylatingA5,
  title={Demethylating agent 5-aza-2'-deoxycytidine activates HLA-G expression in human leukemia cell lines.},
  author={Katar{\'i}na Pol{\'a}kov{\'a} and Elena Band{\vz}uchov{\'a} and D. W. Kuba and Gust{\'a}v Russ},
  journal={Leukemia research},
  year={2009},
  volume={33 4},
  pages={518-24}
}
HLA-G is a non-classical HLA class I antigen primarily expressed in the extravillous cytotrophoblast. HLA-G can also be expressed at some pathological circumstances and may thus contribute to inhibition of efficient immune responses. Complex regulation of HLA-G expression also involves epigenetic mechanisms as DNA methylation. Here we demonstrate that… CONTINUE READING