Dementia with Lewy bodies in a neuropathologic series of suspected Creutzfeldt-Jakob disease.

@article{Hak2000DementiaWL,
  title={Dementia with Lewy bodies in a neuropathologic series of suspected Creutzfeldt-Jakob disease.},
  author={St{\'e}phane Ha{\"i}k and Jean-Philippe Brandel and V{\'e}ronique Sazdovitch and Nicole Delasnerie-Laupr{\^e}tre and Katell H Peoc'h and J L Laplanche and Nicolas Privat and Charles Duyckaerts and Jean Louis K{\'e}m{\'e}ny and Nicolas Kopp and Annie Laquerri{\`e}re and Michel Mohr and J. P. Deslys and Didier Dormont and J. J. Hauw},
  journal={Neurology},
  year={2000},
  volume={55 9},
  pages={1401-4}
}
Discriminating Creutzfeldt-Jakob disease (CJD) from dementia with Lewy bodies (DLB) may be clinically difficult to achieve. The authors describe 10 patients with DLB initially referred to the French Network of Human Spongiform Encephalopathies as having suspected CJD. In a series of 465 autopsied cases, DLB ranked second among degenerative alternative diagnoses to CJD. The authors analyzed the factors that contributed to misleading the diagnosis, and suggest that the detection of 14-3-3 protein… CONTINUE READING

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