Demarcation of Stable Subpopulations within the Pluripotent hESC Compartment

  title={Demarcation of Stable Subpopulations within the Pluripotent hESC Compartment},
  author={Sonam Bhatia and Carlos Pilquil and Ivana Roth-Albin and Jonathan Draper},
  booktitle={PloS one},
Heterogeneity is a feature of stem cell populations, resulting from innate cellular hierarchies that govern differentiation capability. How heterogeneity impacts human pluripotent stem cell populations is directly relevant to their efficacious use in regenerative medicine applications. The control of pluripotency is asserted by a core transcription factor network, of which Oct4 is a necessary member. In mouse embryonic stem cells (ESCs), the zinc finger transcription factor Rex1 (Zfp42) closely… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
3 Extracted Citations
81 Extracted References
Similar Papers

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 81 references

The Coupling of X - Chromosome Inactivation to Pluripotency

  • C Gontan, EM Achame, J Demmers, TS Barakat, E Rentmeester
  • 2012

under physiological oxygen concentrations

  • K Tomoda, K Takahashi, K Leung, A Okada, M Narita
  • 2012

Similar Papers

Loading similar papers…