DeltaPhage—a novel helper phage for high-valence pIX phagemid display

@inproceedings{Nilssen2012DeltaPhageaNH,
  title={DeltaPhage—a novel helper phage for high-valence pIX phagemid display},
  author={Nicolay Rustad Nilssen and Terje Frigstad and Sylvie Pollmann and Norbert Roos and Bjarne Bogen and Inger Sandlie and Geir {\AA}ge L\oset},
  booktitle={Nucleic acids research},
  year={2012}
}
Phage display has been instrumental in discovery of novel binding peptides and folded domains for the past two decades. We recently reported a novel pIX phagemid display system that is characterized by a strong preference for phagemid packaging combined with low display levels, two key features that support highly efficient affinity selection. However, high diversity in selected repertoires are intimately coupled to high display levels during initial selection rounds. To incorporate this… CONTINUE READING
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