Delta9-tetrahydrocannabinol decreases somatic and motivational manifestations of nicotine withdrawal in mice.

@article{Balerio2004Delta9tetrahydrocannabinolDS,
  title={Delta9-tetrahydrocannabinol decreases somatic and motivational manifestations of nicotine withdrawal in mice.},
  author={Graciela N Balerio and Ester As{\'o} and Fernando Berrendero and Patricia Murtra and Rafael Maldonado},
  journal={The European journal of neuroscience},
  year={2004},
  volume={20 10},
  pages={
          2737-48
        }
}
The possible interactions between Delta9-tetrahydrocannabinol (Delta9-THC) and nicotine remain unclear in spite of the current association of cannabis and tobacco in humans. The aim of the present study was to explore the interactions between these two drugs of abuse by evaluating the consequences of Delta9-THC administration on the somatic manifestations and the aversive motivational state associated with nicotine withdrawal in mice. Acute Delta9-THC administration significantly decreased the… CONTINUE READING
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