Delta-like toxin produced by coagulase-negative staphylococci is associated with neonatal necrotizing enterocolitis.

@article{Scheifele1987DeltalikeTP,
  title={Delta-like toxin produced by coagulase-negative staphylococci is associated with neonatal necrotizing enterocolitis.},
  author={David W. Scheifele and Gordean L Bjornson and Robert Anthony Dyer and James E Dimmick},
  journal={Infection and immunity},
  year={1987},
  volume={55 9},
  pages={2268-73}
}
Necrotizing enterocolitis (NEC) is a serious neonatal disorder of uncertain cause, although fecal bacteria have been implicated in some outbreaks. We examined coagulase-negative staphylococci (CONS) as possible etiologic agents. In our unit, CONS colonized the bowels of most infants studied, including 46% of 70 NEC cases (mean concentration, 10(9.1) CFU/g of stool). Over 90% of tested isolates produced a hemolysin resembling delta toxin of Staphylococcus aureus. Toxin purified from a NEC… CONTINUE READING
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