Delta-Aminolaevulinic acid and amino acid neurotransmitters.

@article{Brennan1981DeltaAminolaevulinicAA,
  title={Delta-Aminolaevulinic acid and amino acid neurotransmitters.},
  author={Michael W. Brennan and Richard C. Cantrill},
  journal={Molecular and cellular biochemistry},
  year={1981},
  volume={38 Spec No Pt 1},
  pages={49-58}
}
The effects of the porphyrin precursor delta-aminolaevulinic acid (ALA) on gamma-aminobutyric acid (GABA) and L-glutamate transmitter systems was investigated in rat brain. It was found that ALA inhibited GABA and glutamate uptake and stimulated basal efflux of the amino acids in purified nerve endings. These effects were evident only at relatively high concentrations of ALA (at least 100 microM). Such concentrations probably do not occur in the nervous systems of patients suffering from acute… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

ALA and its clinical impact, from bench to bedside.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology • 2008

Similar Papers

Loading similar papers…