Delivery technologies for genome editing

  title={Delivery technologies for genome editing},
  author={Hao Yin and Kevin J. Kauffman and Daniel G Anderson},
  journal={Nature Reviews Drug Discovery},
With the recent development of CRISPR technology, it is becoming increasingly easy to engineer the genome. Genome-editing systems based on CRISPR, as well as transcription activator-like effector nucleases (TALENs) and zinc-finger nucleases (ZFNs), are becoming valuable tools for biomedical research, drug discovery and development, and even gene therapy. However, for each of these systems to effectively enter cells of interest and perform their function, efficient and safe delivery technologies… CONTINUE READING