Delivery systems for small molecule drugs, proteins, and DNA: the neuroscience/biomaterial interface.

@article{Whittlesey2004DeliverySF,
  title={Delivery systems for small molecule drugs, proteins, and DNA: the neuroscience/biomaterial interface.},
  author={Kevin J Whittlesey and Lonnie D Shea},
  journal={Experimental neurology},
  year={2004},
  volume={190 1},
  pages={1-16}
}
Manipulation of cellular processes in vivo by the delivery of drugs, proteins or DNA is of paramount importance to neuroscience research. Methods for the presentation of these molecules vary widely, including direct injection (either systemic or stereotactic), osmotic pump-mediated chronic delivery, or even implantation of cells engineered to indefinitely secrete a factor of interest. Biomaterial-based delivery systems represent an alternative to more traditional approaches, with the… CONTINUE READING

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