Delivery systems for intradermal vaccination.

  title={Delivery systems for intradermal vaccination.},
  author={Y C Kim and Courtney Jarrahian and Darin Zehrung and Samir Mitragotri and Mark R. Prausnitz},
  journal={Current topics in microbiology and immunology},
Intradermal (ID) vaccination can offer improved immunity and simpler logistics of delivery, but its use in medicine is limited by the need for simple, reliable methods of ID delivery. ID injection by the Mantoux technique requires special training and may not reliably target skin, but is nonetheless used currently for BCG and rabies vaccination. Scarification using a bifurcated needle was extensively used for smallpox eradication, but provides variable and inefficient delivery into the skin… CONTINUE READING

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