Delivery of sry1, but not sry2, to the kidney increases blood pressure and sns indices in normotensive wky rats


Our laboratory has shown that a locus on the SHR Y chromosome increases blood pressure (BP) in the SHR rat and in WKY rats with the SHR Y chromosome (SHR/y rat). A candidate for this Y chromosome hypertension locus is Sry, a gene that encodes a transcription factor responsible for testes determination. The SHR Y chromosome has six divergent Sry loci. The… (More)
DOI: 10.1186/1472-6793-9-10


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