Delivery of recombinant gene product to canine brain with the use of microencapsulation.

@article{Barsoum2003DeliveryOR,
  title={Delivery of recombinant gene product to canine brain with the use of microencapsulation.},
  author={Susan C Barsoum and William N Milgram and William C. Mackay and Craig L Coblentz and Kathleen H Delaney and Jacek M Kwiecien and Stephen A. Kruth and Patricia L. Y. Chang},
  journal={The Journal of laboratory and clinical medicine},
  year={2003},
  volume={142 6},
  pages={399-413}
}
An alternative approach to somatic gene therapy is to deliver a therapeutic protein by implanting "universal" recombinant cells that are immunologically protected from graft rejection with alginate microcapsules. This strategy has proved successful in reversing pathologic conditions in several rodent models of human disease (dwarfism, lysosomal storage… CONTINUE READING