Delivery of noncarrier naked DNA vaccine into the skin by supersonic flow induces a polarized T helper type 1 immune response to cancer.

Abstract

BACKGROUND DNA vaccine is a new and powerful approach to generate immunological responses against infectious disease and cancer. The T helper type (Th)1 immune response is usually required for generating effective anti-tumor responses. A microparticulate bombardment system can induce an immune response using very low amounts of DNA. Using nozzle… (More)
DOI: 10.1002/jgm.1183

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Cite this paper

@article{Lin2008DeliveryON, title={Delivery of noncarrier naked DNA vaccine into the skin by supersonic flow induces a polarized T helper type 1 immune response to cancer.}, author={Chi-Chen Lin and Meng-Chi Yen and Chiu-Mei Lin and Shih-Shien Huang and Huei-Jiun Yang and N H Chow and M. C. S. Lai}, journal={The journal of gene medicine}, year={2008}, volume={10 6}, pages={679-89} }