Delivery of neurotrophin-3 from fibrin enhances neuronal fiber sprouting after spinal cord injury.

@article{Taylor2006DeliveryON,
  title={Delivery of neurotrophin-3 from fibrin enhances neuronal fiber sprouting after spinal cord injury.},
  author={Sara J Taylor and Ephron S. Rosenzweig and John W. Mcdonald and Shelly E Sakiyama-Elbert},
  journal={Journal of controlled release : official journal of the Controlled Release Society},
  year={2006},
  volume={113 3},
  pages={
          226-35
        }
}
  • Sara J Taylor, Ephron S. Rosenzweig, +1 author Shelly E Sakiyama-Elbert
  • Published in
    Journal of controlled release…
    2006
  • Chemistry, Medicine
  • Neurotrophins have been shown to promote axonal growth and regeneration after spinal cord injury. The therapeutic utility of neurotrophins may be enhanced by using a controlled delivery system to increase the duration of neurotrophin availability following injury. Such a delivery system can be incorporated into a bioactive scaffold to serve as a physical bridge for regeneration. This study assessed the effect of controlled delivery of neurotrophin-3 (NT-3) from fibrin scaffolds implanted in… CONTINUE READING

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