Delivery of a Cell Patch of Cocultured Endothelial Cells and Smooth Muscle Cells Using Thermoresponsive Hydrogels for Enhanced Angiogenesis.

@article{Bak2016DeliveryOA,
  title={Delivery of a Cell Patch of Cocultured Endothelial Cells and Smooth Muscle Cells Using Thermoresponsive Hydrogels for Enhanced Angiogenesis.},
  author={Seongwoo Bak and Taufiq Ahmad and Yu Bin Lee and Joong-yup Lee and Eun Mi Kim and Heungsoo Shin},
  journal={Tissue engineering. Part A},
  year={2016},
  volume={22 1-2},
  pages={182-93}
}
Cell-based therapy has been studied as an attractive strategy for therapeutic angiogenesis. However, obtaining a stable vascular structure remains a challenge due to the poor interaction of transplanted cells with native tissue and the difficulty in selecting the optimal cell source. In this study, we developed a cell patch of cocultured human umbilical vein endothelial cells (HUVECs) and smooth muscle cells (SMCs) using thermosensitive hydrogels for regeneration of mature vasculatures. In… CONTINUE READING