Delivering instilled hydrophobic drug to the bladder by a cationic nanoparticle and thermo-sensitive hydrogel composite system.

Abstract

Some bladder disease therapies can benefit from intravesical drug delivery, which involves direct instillation of drug into the bladder via a catheter, to attain high local concentrations of the drug with minimal systemic effects. Deguelin is a potential anticancer agent, however, its poor water solubility and neurotoxicity restrict its clinical application… (More)

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@article{Men2012DeliveringIH, title={Delivering instilled hydrophobic drug to the bladder by a cationic nanoparticle and thermo-sensitive hydrogel composite system.}, author={Ke Men and Wei Liu and Lin Li and Xingmei Duan and Pan Wang and Maling Gou and Xiawei Wei and Xiang Gao and Bilan Wang and Yanan Du and Meijuan Huang and Lijuan Chen and Zhiyong Qian and Yu-Quan Wei}, journal={Nanoscale}, year={2012}, volume={4 20}, pages={6425-33} }