Delirium in older persons.

  title={Delirium in older persons.},
  author={Sharon K. Inouye},
  journal={The New England journal of medicine},
  volume={354 11},
  • S. Inouye
  • Published 16 March 2006
  • Medicine, Psychology
  • The New England journal of medicine
The prevalence of delirium increases sharply with age, and about 20 percent of older patients have delirium at the time of hospital admission for any reason. This review summarizes the clinical manifestations of and risk factors for delirium and the evaluation of patients with this condition. It includes an update on the current understanding of the pathogenesis of delirium and provides guidance regarding practical measures to prevent this common complication. 

Tables from this paper

Delirium in Older Adults

This chapter reviews the etiology, consequences, screening, diagnosis, prevention, and management of delirium in older patients.

An overview of delirium for the community and hospital clinician

Risk factors for delirium, symptoms, how to diagnose and manage deliria, and finally, what prospects prognosis can hold are described.

Postoperative delirium in the elderly: diagnosis and management

The diagnosis and treatment of postoperative delirium with environmental, supportive, and pharmacologic interventions reduces the incidence and side effects of postoperatively delirious patients.

Diagnosis and Management of Delirium

This chapter will review the presentation, diagnosis, and management of delirium.

Delirium: A focused review

  • H. Kirshner
  • Psychology, Medicine
    Current neurology and neuroscience reports
  • 2007
The clinical features, etiology, clinical evaluation, and treatment of delirium during hospitalization are reviewed.

Drugs, Delirium and Older People

This review explores the relationship between drugs and delirium based on the understanding of the neuropathology and neurotransmitter hypothesis ofdelirium and the limitations of the evidence that certain drugs are causative or useful in the treatment and prevention of deliria.

Assessment and management of delirium in the older adult with cancer.

  • S. Derby
  • Medicine, Psychology
    Clinical journal of oncology nursing
  • 2011
Oncology nurses caring for older patients with cancer have the opportunity to recognize the onset of delirium, provide ongoing patient assessment and monitoring, and implement pharmacologic and nonpharmacologic interventions.

Delirium in trauma

The current understanding of delirium is discussed with specific reference to trauma patients, as it is associated with an increase in mortality as well as cognitive and functional decline, increased length of hospital stay and increased risk of institutionalisation on discharge.

Delirium in elderly general medical inpatients: a prospective study

The aim of the study was to determine the prevalence and incidence of delirium in older medical inpatients in a metropolitan teaching hospital, the incidence of known risk factors and current practice in identifying and managing patients at risk of this condition.

Postoperative delirium among older people

This condition should be considered as a syndrome of epidemiological importance, which needs to be prevented or treated in a timely manner through a multidisciplinary intervention.



Delirium in hospitalized older patients.

  • S. Inouye
  • Medicine, Psychology
    Clinics in geriatric medicine
  • 1998

Delirium in old age

The concept of delirium: historical antecedents and present meanings, and the role of families, family caregivers and nurses in education and management.

Etiology and Management of Delirium

The epidemiology, risk factors, interventions, causes, management, and outcomes of delirium are discussed and the pathophysiology has the potential to radically alter the management of Delirium.

Progression and Resolution of Delirium in Elderly Patients Hospitalized for Acute Care.

  • S. LevkoffB. Liptzin J. Rowe
  • Medicine, Psychology
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
  • 1994
Clinical evidence of delirium frequently persisted after hospital discharge although there was evidence of lessening of the extent of symptoms over time, which has implications for discharge planners concerned with providing appropriate supports for those still experiencing deliral symptoms at the time of hospital discharge.

Delirium in the Hospitalised Elderly

There is an inverse relationship between patient vulnerability and the severity of insult required to induce delirium, and although previously considered to be a self-limiting condition, complete reversal is the exception rather than the rule.

Delirium. The occurrence and persistence of symptoms among elderly hospitalized patients.

It is suggested that delirium is a common disorder that may be substantially less transient than currently believed and that incomplete manifestations of the syndrome may be frequent.

Delirium in the terminally ill.

Immunology of delirium: new opportunities for treatment and research

Delirium is a common clinical syndrome that presents in a wide variety of physical conditions and is associated with a poor prognosis and prospective studies on elderly hospitalised medical patients demonstrate outcomes.

Delirium in elderly patients.

  • M. Cole
  • Medicine, Psychology
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
  • 2004
Although there has been limited progress in understanding the etiology, pathogenesis, assessment, and specific treatment of delirium, systematic detection and treatment programs appear to be beneficial for elderly surgical patients, as are preventive programs for elderly medical and surgical patients.

Delirium in older medical inpatients and subsequent cognitive and functional status: a prospective study.

For older patients with and without dementia, delirium is an independent predictor of sustained poor cognitive and functional status during the year after a medical admission to hospital.