Delipidation of a hepadnavirus: Viral inactivation and vaccine development.

Abstract

Many viruses including HIV, hepatitis C and hepatitis B, have an outer lipid envelope which maintains inserted viral peptides in the "correct" functional conformation and orientation. Disruption of the lipid envelope by most solvents destroys infectivity and often results in a loss of antigenicity. This communication outlines a novel approach to viral… (More)

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Cite this paper

@article{Cham2006DelipidationOA, title={Delipidation of a hepadnavirus: Viral inactivation and vaccine development.}, author={Bill Elliot Cham and Katherine Diaz Vickery and Rahma Tohidi-Esfahani and Yvonne E Cossart}, journal={Journal of virological methods}, year={2006}, volume={137 1}, pages={160-3} }