Delineation of the recombination sites necessary for integration of pathogenicity islands II and III into the Escherichia coli 536 chromosome.

@article{Wilde2008DelineationOT,
  title={Delineation of the recombination sites necessary for integration of pathogenicity islands II and III into the Escherichia coli 536 chromosome.},
  author={Caroline Wilde and Didier Mazel and Bianca Hochhut and Barbara Middendorf and Fr{\'e}d{\'e}rique Le Roux and Elisabeth Carniel and Ulrich Dobrindt and Joerg Hacker},
  journal={Molecular microbiology},
  year={2008},
  volume={68 1},
  pages={139-51}
}
In uropathogenic Escherichia coli strain 536, six pathogenicity islands (PAIs) encode key virulence factors. All PAIs except PAI IV(536) are flanked by direct repeats and four of them encode integrases responsible for their chromosomal excision. To study recombination sites used for the integration by PAI II(536) and III(536) integrases, we measured site-specific recombination between the chromosomal integration site attB, and the PAI-specific attachment site attP. We show that PAI III(536… CONTINUE READING

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