Delineation of the molecular basis of delta- and normal HbA2 beta-thalassemia.

@article{Moi1988DelineationOT,
  title={Delineation of the molecular basis of delta- and normal HbA2 beta-thalassemia.},
  author={Paolo Moi and Elisabetta Paglietti and Alessandra Sanna and Carlo Brancati and Antonio Tagarelli and Renzo Galanello and Antonio Cao and Mario Pirastu},
  journal={Blood},
  year={1988},
  volume={72 2},
  pages={530-3}
}
In this study, we used cloning and sequence analysis to define the molecular defect in two delta-thalassemia genes, one associated with reduced output of delta-globin chains (delta +thal) from a Sardinian and the other with a complete suppression of delta-chain production from the affected locus (delta zerp thal) from a Southern Italian. Sequence analysis… CONTINUE READING