Delineation of downstream signalling components during acrosome reaction mediated by heat solubilized human zona pellucida

@inproceedings{Bhandari2010DelineationOD,
  title={Delineation of downstream signalling components during acrosome reaction mediated by heat solubilized human zona pellucida},
  author={Beena Bhandari and Pankaj Bansal and Pankaj Talwar and Satish Kumar Gupta},
  booktitle={Reproductive biology and endocrinology : RB&E},
  year={2010}
}
BACKGROUND Human egg is enveloped by a glycoproteinaceous matrix, zona pellucida (ZP), responsible for binding of the human spermatozoa to the egg and induction of acrosomal exocytosis in the spermatozoon bound to ZP. In the present manuscript, attempts have been made to delineate the downstream signalling components employed by human ZP to induce acrosome reaction. METHODS Heat-solubilized human ZP (SIZP) was used to study the induction of acrosome reaction in capacitated human spermatozoa… CONTINUE READING

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