Delineating the antigenotoxic and anticytotoxic potentials of 4-methylimidazole against ethyl methanesulfonate toxicity in bone marrow cell of swiss albino mice.

@article{Tazehkand2016DelineatingTA,
  title={Delineating the antigenotoxic and anticytotoxic potentials of 4-methylimidazole against ethyl methanesulfonate toxicity in bone marrow cell of swiss albino mice.},
  author={Mostafa Norizadeh Tazehkand and Mehmet Topaktaş and Mehmet Bertan Yilmaz and O Hajipour and Ebrahim Valipour},
  journal={Bratislavske lekarske listy},
  year={2016},
  volume={117 5},
  pages={290-4}
}
4-Methylimidazole (4-MEI) is mostly used in beverages and coloring food, dark beers and common brands of cola drinks, which may contain more than 100 μg of this compound per 12-ounce serving. This study was aimed to investigate the antigenotoxic and anticytotoxic effects of 4-MEI (100, 130 and 160 mg/kg) against ethyl methanesulfonate (240 mg/kg) using chromosome aberrations (CAs) and Mitotic index (MI) tests in bone marrow cells of Swiss Albino Mice at 12 h and 24 h treatment periods. So, the… CONTINUE READING