Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization.

Abstract

Serum characterization and antibody isolation are transforming our understanding of the humoral immune response to viral infection. Here, we show that epitope specificities of HIV-1-neutralizing antibodies in serum can be elucidated from the serum pattern of neutralization against a diverse panel of HIV-1 isolates. We determined "neutralization fingerprints… (More)
DOI: 10.1126/science.1233989

Topics

4 Figures and Tables

Slides referencing similar topics