Delineating Genetic Alterations for Tumor Progression in the MCF10A Series of Breast Cancer Cell Lines

@inproceedings{Kadota2010DelineatingGA,
  title={Delineating Genetic Alterations for Tumor Progression in the MCF10A Series of Breast Cancer Cell Lines},
  author={Mitsutaka Kadota and Howard Hua Yang and Bianca P Gomez and Misako Sato and Robert J. Clifford and Daoud Meerzaman and Barbara K. Dunn and Lalage M. Wakefield and Maxwell P. Lee},
  booktitle={PloS one},
  year={2010}
}
To gain insight into the role of genomic alterations in breast cancer progression, we conducted a comprehensive genetic characterization of a series of four cell lines derived from MCF10A. MCF10A is an immortalized mammary epithelial cell line (MEC); MCF10AT is a premalignant cell line generated from MCF10A by transformation with an activated HRAS gene; MCF10CA1h and MCF10CA1a, both derived from MCF10AT xenografts, form well-differentiated and poorly-differentiated malignant tumors in the… CONTINUE READING
70 Citations
22 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 70 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 22 references

Similar Papers

Loading similar papers…