Deletions of 17p and p53 mutations in preneoplastic lesions of the lung.

@article{Sozzi1992DeletionsO1,
  title={Deletions of 17p and p53 mutations in preneoplastic lesions of the lung.},
  author={Gabriella Sozzi and Monica Miozzo and Rosangela Donghi and Silvana Pilotti and C T Cariani and Ugo Pastorino and G D Della Porta and Marco Alessandro Pierotti},
  journal={Cancer research},
  year={1992},
  volume={52 21},
  pages={6079-82}
}
Cytogenetic and p53 mutation analysis in two cases of severe dysplasia of the bronchial epithelium in lung cancer patients and p53 immunostaining in a third one are reported. The finding of both chromosomal deletions of 17p and p53 mutation indicates that these changes may take place early in the process of lung carcinogenesis. 

Citations

Publications citing this paper.
Showing 1-10 of 62 extracted citations

Multiple primary lung cancer: A literature review.

Advances in clinical and experimental medicine : official organ Wroclaw Medical University • 2018

References

Publications referenced by this paper.
Showing 1-10 of 25 references

Wild-typebut not mutant p53 suppressesthe growth of human lung cancer cells bearing multiple genetic lesions. Cancer 6081 b 3, T @\ AG CT T\ †̃@z TI AL codonl6l c

T. Takahashi, D. Carbone, +5 authors D i.
AlaiThr L/@;i i;.: . on April • 1992
View 4 Excerpts
Highly Influenced

Application of PCR-RFLP analysis to allele loss studies in small biopsies oflung tumors and preinvasive lesions of the lung

P. H. Rabbitts, V. Sundaresan, +3 authors G. Sinha
Third European Workshop on Cytogenetics and Molecular Genetics ofHuman Solid Tumors. Porto, April 26-29, • 1992
View 1 Excerpt

L Genetic alterations during colorectaltumordevelopment

B. Vogelstein, E. R. Fearon, +7 authors J. Bos
N . Engl . J . Med . • 1992

Mutations ofp 53 and rat genes in radon associated lung cancer from uranium miners

J. M. Samet, R. A. Metcalf, +3 authors C. C. Harris
Lancet • 1992

Mutations ofp53 and rat genes in radon associated lung cancer from uranium

K. H. Vähãkangas, J. M. Samet, +4 authors C. C. Harris
miners. Lancet, • 1992
View 2 Excerpts

Similar Papers

Loading similar papers…