Deletions generated by the transposon Tn10 in the srl recA region of the Escherichia coli K-12 chromosome.

@article{Csonka1979DeletionsGB,
  title={Deletions generated by the transposon Tn10 in the srl recA region of the Escherichia coli K-12 chromosome.},
  author={Laszlo N Csonka and Alvin J. Clark},
  journal={Genetics},
  year={1979},
  volume={93 2},
  pages={321-43}
}
A negative regulatory gene for the srl operon (srlR) was recognized by the characteristics of an insertion mutation generated by the transposon Tn10 determining tetracycline resistance. This finding is discussed in light of previous hypotheses on the regulation of the srl genes, which mediate metabolism of glucitol (i.e., sorbitol). Mapping showed that the order of genes in this region is: srlR srlD srlC recA alaS. Using two different methods, five mutations of both srl and recA were detected… CONTINUE READING
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Analysis of the regulatory mechanisms controlling the synthesis of the hexitol transport systems in Echerichia coli

  • K. MCENTEE
  • Mol . Gen . Genet .
  • 1978

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