Deletion of synapsins I and II genes alters the size of vesicular pools and rabphilin phosphorylation.

@article{Lonart2006DeletionOS,
  title={Deletion of synapsins I and II genes alters the size of vesicular pools and rabphilin phosphorylation.},
  author={Gy{\"o}rgy Lonart and Fatma Simsek-Duran},
  journal={Brain research},
  year={2006},
  volume={1107 1},
  pages={42-51}
}
Previous studies established that genetic deletion of synapsins, synaptic vesicle-associated phosphoproteins that regulate neurotransmitter release, decreases the number of synaptic vesicles in nerve terminals. To investigate whether these changes affect the release properties of the remaining synaptic vesicles, we used a radioactive labeling technique to measure release independently of the total number of synaptic vesicles. 3H-glutamate and 14C-gamma-amino-butyric-acid (GABA) release from… CONTINUE READING

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