Deletion of endothelial cell endothelin B receptors does not affect blood pressure or sensitivity to salt.

@article{Bagnall2006DeletionOE,
  title={Deletion of endothelial cell endothelin B receptors does not affect blood pressure or sensitivity to salt.},
  author={Alan J Bagnall and Nicholas F Kelland and Fiona Gulliver-Sloan and Anthony P. Davenport and Gillian A Gray and Masashi Yanagisawa and David J. Webb and Yuri V. Kotelevtsev},
  journal={Hypertension},
  year={2006},
  volume={48 2},
  pages={286-93}
}
Endothelin B receptors in different tissues regulate diverse physiological responses including vasoconstriction, vasodilatation, clearance of endothelin-1, and renal tubular sodium reabsorption. To examine the role of endothelial cell endothelin B receptors in these processes, we generated endothelial cell-specific endothelin B receptor knockout mice using a Cre-loxP approach. We have demonstrated loss of endothelial cell endothelin B receptor expression and function and preservation of… CONTINUE READING
34 Citations
44 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 34 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 44 references

produced by chronic ET - 1

  • JM Williams, JS Pollock, DM Pollock
  • 2005

Similar Papers

Loading similar papers…