Deletion of a chaperonin 60 beta gene leads to cell death in the Arabidopsis lesion initiation 1 mutant.

@article{Ishikawa2003DeletionOA,
  title={Deletion of a chaperonin 60 beta gene leads to cell death in the Arabidopsis lesion initiation 1 mutant.},
  author={Atsushi Ishikawa and Hideaki Tanaka and Masato Nakai and T Masaki Asahi},
  journal={Plant & cell physiology},
  year={2003},
  volume={44 3},
  pages={
          255-61
        }
}
Lesion mimic mutants develop spontaneous cell death without pathogen attack. Some of the genes defined by these mutations may function as regulators of cell death, whereas others may perturb cellular metabolism in a way that leads to cell death. To understand the molecular mechanism of cell death in lesion mimic mutants, we isolated a lesion initiation 1 (len1) mutant by a T-DNA tagging method. The len1 mutant develops lesions on its leaves and expresses systemic acquired resistance (SAR). LEN1… CONTINUE READING
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