Deletion of Plasmodium berghei-specific CD4+ T cells adoptively transferred into recipient mice after challenge with homologous parasite.

@article{Hirunpetcharat1998DeletionOP,
  title={Deletion of Plasmodium berghei-specific CD4+ T cells adoptively transferred into recipient mice after challenge with homologous parasite.},
  author={Chakrit Hirunpetcharat and Michael F Good},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1998},
  volume={95 4},
  pages={1715-20}
}
The immune response to malaria parasites includes T cell responses that reduce parasites by effector T cell responses and by providing help for antibody responses. Some parasites are more sensitive to antibody and others are more sensitive to cell-mediated immunity. We demonstrate that cultured CD4(+) T cells that produce interferon gamma and interleukin 2, but not interleukin 4, in response to stimulation with the rodent parasite Plasmodium berghei can reduce but not eliminate parasites in… CONTINUE READING

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Parasite Immu- nol

A. W. Taylor-Robinson, R. S. Phillips
1993

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