Deletion of Glucocorticoid Receptors in Forebrain GABAergic Neurons Alters Acute Stress Responding and Passive Avoidance Behavior in Female Mice

@inproceedings{Scheimann2018DeletionOG,
  title={Deletion of Glucocorticoid Receptors in Forebrain GABAergic Neurons Alters Acute Stress Responding and Passive Avoidance Behavior in Female Mice},
  author={Jessie R Scheimann and Parinaz Mahbod and Rachel L. Morano and Lindsey Frantz and Ben Packard and Kenneth Campbell and James P Herman},
  booktitle={Front. Behav. Neurosci.},
  year={2018}
}
The glucocorticoid receptor (GR) is critically involved in regulation of stress responses [inhibition of the hypothalamic-pituitary-adrenal (HPA) axis], emotional behavior and cognition via interactions with forebrain corticolimbic circuity. Work to date has largely focused on GR actions in forebrain excitatory neurons; however, recent studies suggest a potential role mediated by interneurons. Here, we targeted GR deletion in forebrain GABAergic neurons, including the cortical interneurons… CONTINUE READING
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