• Biology, Medicine
  • Published in
    Asian Pacific journal of…
    2011

Deletion of Forkhead Box M1 transcription factor reduces malignancy in laryngeal squamous carcinoma cells.

@article{Chen2011DeletionOF,
  title={Deletion of Forkhead Box M1 transcription factor reduces malignancy in laryngeal squamous carcinoma cells.},
  author={Wei Chen and Kun Yuan and Ze-zhang Tao and Bo-kui Xiao},
  journal={Asian Pacific journal of cancer prevention : APJCP},
  year={2011},
  volume={12 7},
  pages={
          1785-8
        }
}
The transcription factor, Forkhead Box M1 (FoxM1), has a specific expression pattern during the cell cycle. It also plays an important role in cellular developmental pathways and in the maintenance of homeostasis between cell proliferation and apoptosis. However, the precise role and molecular mechanisms associated with FoxM1 in laryngeal squamous carcinoma remain unclear. Therefore, laryngeal squamous carcinoma cells were transfected with FoxM1-targeted small interfering RNA (siRNA) and… CONTINUE READING

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