Deletion of Epstein-Barr virus latent membrane protein 1 gene in Japanese and Brazilian gastric carcinomas, metastatic lesions, and reactive lymphocytes.

@article{Hayashi1998DeletionOE,
  title={Deletion of Epstein-Barr virus latent membrane protein 1 gene in Japanese and Brazilian gastric carcinomas, metastatic lesions, and reactive lymphocytes.},
  author={Katsuo Hayashi and Weina Chen and Yunn Yi Chen and Ichiro Murakami and Hui Ling Chen and Nobuya Ohara and Soichiro Nose and Kazuo Hamaya and Shinobu Matsui and Maura Moscardi Bacchi and Carlos Eduardo Bacchi and Karen L Chang and Lawrence M. Weiss},
  journal={The American journal of pathology},
  year={1998},
  volume={152 1},
  pages={191-8}
}
A 30-bp deletion in the Epstein-Barr virus (EBV) latent membrane protein 1 (LMP1) gene has been reported in nasopharyngeal carcinoma and EBV-associated malignant lymphomas. Information on this deletion in EBV-associated gastric carcinoma (EBVaGC) is limited. The association of gastric carcinoma (GC) with EBV was examined by EBV-encoded RNA (EBER) in situ hybridization in 510 patients from Japan and 80 patients from Brazil. We studied the prevalence of 30-bp LMP1 gene deletion in EBVaGC in Japan… CONTINUE READING