Deletion of 7q31.1 supports involvement of FOXP2 in language impairment: Clinical report and review

@article{Lennon2007DeletionO7,
  title={Deletion of 7q31.1 supports involvement of FOXP2 in language impairment: Clinical report and review},
  author={Patrick A. Lennon and Mitchell Lance Cooper and Daniel A. Peiffer and Kevin L. Gunderson and A. Patel and Sarika U. Peters and Sau Wai Cheung and Carlos A. Bacino},
  journal={American Journal of Medical Genetics Part A},
  year={2007},
  volume={143A}
}
We report on a young male with moderate mental retardation, dysmorphic features, and language delay who is deleted for 7q31.1‐7q31.31. His full karyotype is 46,XY,der(7)del(7)(q31.1q31.31)ins(10;7)(q24.3;q31.1q31.31)mat. This child had language impairment, including developmental verbal dyspraxia, but did not meet criteria for autism according to standardized ADOS testing. Our patient's deletion, which is the smallest reported deletion including FOXP2, adds to the body of evidence that supports… 

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