Deletion mapping of chromosome 11 in carcinoma of the bladder.

  title={Deletion mapping of chromosome 11 in carcinoma of the bladder.},
  author={Margaret E. Shaw and Margaret A Knowles},
  journal={Genes, chromosomes & cancer},
  volume={13 1},
Deletions of the short arm of chromosome 11 have been identified by both cytogenetic and molecular criteria in bladder and other types of solid tumor, indicating the presence of one or more suppressor loci in this region. To localize the 11p deletion target(s) more precisely and to screen for loss of heterozygosity (LOH) on the long arm of the chromosome, 100 bladder tumors were analyzed for LOH on chromosome 11 using restriction fragment length polymorphisms (RFLPs) and microsatellite markers… CONTINUE READING
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