Deletion in the genes encoding outer surface proteins OspA and OspB of Borrelia garinii isolated from patients in Japan.

@article{Wang1997DeletionIT,
  title={Deletion in the genes encoding outer surface proteins OspA and OspB of Borrelia garinii isolated from patients in Japan.},
  author={Jian-gang Wang and Toshiyuki Masuzawa and Martin Man-chun Li and Yasutake Yanagihara},
  journal={Microbiology and immunology},
  year={1997},
  volume={41 9},
  pages={
          673-9
        }
}
We detected the expression of outer surface proteins OspA and OspB, and characterized the genes encoding the two Osps of eight Borrelia garinii isolates from patients in Japan. Six of the eight strains shared a common antigenic epitope in their OspA and/or OspB proteins to monoclonal antibody P3134 against OspB, and were identified to have a conserved carboxyl terminus on their ospA and ospB genes by Southern blot hybridization. One strain, JEM4, did not express OspB protein, which was due to… CONTINUE READING
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