Deletion formation in bacteriophage T4.

@article{Singer1988DeletionFI,
  title={Deletion formation in bacteriophage T4.},
  author={Britta Swebilius Singer and J Westlye},
  journal={Journal of molecular biology},
  year={1988},
  volume={202 2},
  pages={
          233-43
        }
}
We have manipulated the dispensable region of the rIIB gene of bacteriophage T4 in order to study the generation of deletions involving direct repeats. We show that recombination between different parental chromosomes is one source of the deletions we have studied. We have also investigated the effects of structure, base composition and distance on deletion formation. We demonstrate that the potential to form structure in single-stranded DNA has variable effects on the frequency of deletion… CONTINUE READING
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