Deleterious effects of high-fat diet on perinatal and postweaning periods in adult rat offspring.

@article{Parente2008DeleteriousEO,
  title={Deleterious effects of high-fat diet on perinatal and postweaning periods in adult rat offspring.},
  author={Lyana Barbosa Parente and M{\'a}rcia Barbosa {\'A}guila and Carlos Alberto Mandarim-de-Lacerda},
  journal={Clinical nutrition},
  year={2008},
  volume={27 4},
  pages={623-34}
}
BACKGROUND & AIMS Pre- and postnatal environmental changes can reset the developmental path during intrauterine development leading to obesity and cardiovascular and metabolic disorders later in life. The effects of high-fat diets on body mass, fat mass, the plasma level of glucose, insulin and leptin, as well as the insulin/glucose ratio and cardiovascular parameters in adult rat offspring were studied. METHODS Pregnant Wistar rats in a standard chow group (SC) or high-fat chow group (HFC… CONTINUE READING

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