Deleterious effect of prednisolone in HBsAg-positive chronic active hepatitis.

@article{Lam1981DeleteriousEO,
  title={Deleterious effect of prednisolone in HBsAg-positive chronic active hepatitis.},
  author={Kwok Chi Lam and C. L. Lai and Christian Tr{\'e}po and P. C. Wu},
  journal={The New England journal of medicine},
  year={1981},
  volume={304 7},
  pages={380-6}
}
To study the efficacy of corticosteroids in chronic active hepatitis (CAH) positive for hepatitis B surface antigen (HBsAg), we pair-randomized 51 patients to receive either 15 to 20 mg of prednisolone per day or a placebo. After initial remission, the maintenance dosage of prednisolone was 10 mg per day, and the patients were prospectively followed for up… CONTINUE READING