Delayed-type hypersensitivity reaction to ethambutol and isoniazid.

  title={Delayed-type hypersensitivity reaction to ethambutol and isoniazid.},
  author={R S L A Bakkum and F B D E Waard-Van Der Spek and Hok Bing Thio},
  journal={Contact dermatitis},
  volume={46 6},
A 24-year-old woman had recently started antitubercular therapy with isoniazid, ethambutol and rifampicin. This therapy was discontinued 2 weeks later due to an itchy, desquamative, erythematous, papular rash, with painful crusts and excoriations, spreading from the face and hands to the rest of the body. 5days after withdrawal of all drugs, widespread desquamation and exfoliation with predilection for the body folds and the peri-orbital and peri-oral regions occurred, with swelling of the… CONTINUE READING


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