Delayed spongiform leukoencephalopathy after heroin abuse

  title={Delayed spongiform leukoencephalopathy after heroin abuse},
  author={Nicolo' Rizzuto and Michela Morbin and Sergio Ferrari and Tiziana L Cavallaro and Marco Sparaco and Giulio Boso and Luigi Gaetti},
  journal={Acta Neuropathologica},
Here we report the clinical and pathological findings in a 30-year-old drug addict in whom an intravenous injection of heroin led to reversible coma with respiratory depression and heart failure. On regaining consciousness, the patient was found to have rhabdomyolysis with renal failure requiring dialysis and peripheral neuropathy. Three weeks later his neurological condition suddenly deteriorated and delayed encephalopathy developed, leading to death 20 days later. The neuropathological study… CONTINUE READING
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