Delayed riluzole treatment is able to rescue injured rat spinal motoneurons.

  title={Delayed riluzole treatment is able to rescue injured rat spinal motoneurons.},
  author={Antal N{\'o}gr{\'a}di and Andr{\'a}s Szab{\'o} and S{\'a}ndor Pint{\'e}r and Gerta Vrb{\'o}va},
  volume={144 2},
The effect of delayed 2-amino-6-trifluoromethoxy-benzothiazole (riluzole) treatment on injured motoneurons was studied. The L4 ventral root of adult rats was avulsed and reimplanted into the spinal cord. Immediately after the operation or with a delay of 5, 10, 14 or 16 days animals were treated with riluzole (n=5 in each group) while another four animals remained untreated. Three months after the operation the fluorescent dye Fast Blue was applied to the proximal end of the cut ventral ramus… CONTINUE READING

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