Delayed repair of transected nerves: effect of brain-derived neurotrophic factor.


OBJECTIVE To determine if administration of brain-derived neurotrophic factor (BDNF) after peripheral nerve transection can improve the functional outcome in situations where epineurial repair must be delayed. DESIGN Randomized, blinded, controlled trial. SUBJECTS Thirty-four Sprague-Dawley rats. INTERVENTION Sciatic nerves were transected and, after… (More)


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