Delayed rectifier outward K+ current mediates the migration of rat cerebellar granule cells stimulated by melatonin.

Abstract

Melatonin (MT) may work as a neuromodulator through the associated MT receptors in the central nervous system. Previously, our studies have shown that MT increased the I(K) current via a G protein-related pathway. In the present study, patch-clamp whole-cell recording, transwell migration assays and organotypic cerebellar slice cultures were used to examine… (More)

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