Delayed rectification in the transverse tubules: origin of the late after-potential in frog skeletal muscle

Abstract

Tetanic stimulation of skeletal muscle fibers elicits a train of spikes followed by a long-lasting depolarization called the late after-potential (LAP). We have conducted experiments to determine the origin of the LAP. Isolated single muscle fibers were treated with a high potassium solution (5 mM or 10 mM K) followed by a sudden reduction of potassium… (More)

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@article{Kirsch1977DelayedRI, title={Delayed rectification in the transverse tubules: origin of the late after-potential in frog skeletal muscle}, author={Glenn E. Kirsch and Robert A. Nichols and Shigehiro Nakajima}, journal={The Journal of General Physiology}, year={1977}, volume={70}, pages={1 - 21} }