Delayed radiation necrosis with extensive brain edema after gamma knife radiosurgery for multiple cerebral cavernous malformations--case report.

@article{Takenaka2003DelayedRN,
  title={Delayed radiation necrosis with extensive brain edema after gamma knife radiosurgery for multiple cerebral cavernous malformations--case report.},
  author={Nobuo Takenaka and Tomoyuki Imanishi and Hikaru Sasaki and Kenji Shimazaki and Hitoshi Sugiura and Yasuhisa Kitagawa and Sari Sekiyama and Masaaki Yamamoto and Takahito Kazuno},
  journal={Neurologia medico-chirurgica},
  year={2003},
  volume={43 8},
  pages={391-5}
}
A 39-year-old man presented with multiple intracranial cavernous malformations manifesting as intractable seizures persisting for more than 20 years. He underwent gamma knife radiosurgery (GKRS) for right frontal and left temporal cavernous malformations. He began to suffer from progressive left hemiparesis and inattention 2 years 5 months after the GKRS. Magnetic resonance imaging showed abnormal ring enhancement and extensive brain edema around the right frontal lesion. Conservative therapies… CONTINUE READING

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