Delayed protective effects of hyperoxia against cardiac arrhythmias and infarction in anesthetized rats.

BACKGROUND Previous studies have shown that pretreatment with normobaric hyperoxia has cardioprotective effect in isolated rat heart. The present study was designed to test the hypothesis that pretreatment normobaric hyperoxia could induce delayed cardioprotection effect in an in vivo regional heart ischemia. MATERIALS AND METHODS Experiment 1: Rats were… CONTINUE READING