Delayed priming promotes CNS regeneration post-rhizotomy in Neurocan and Brevican-deficient mice.

@article{Quaglia2008DelayedPP,
  title={Delayed priming promotes CNS regeneration post-rhizotomy in Neurocan and Brevican-deficient mice.},
  author={Xavier Quaglia and Ahmed T. Beggah and Constanze I. Seidenbecher and Anne D. Zurn},
  journal={Brain : a journal of neurology},
  year={2008},
  volume={131 Pt 1},
  pages={240-9}
}
A wealth of literature has provided evidence that reactive tissue at the site of CNS injury is rich in chondroitin sulfate proteoglycans which may contribute to the non-permissive nature of the CNS. We have recently demonstrated using a murine model of human brachial plexus injury that the chondroitin sulfate proteoglycans Neurocan and Brevican are differentially expressed by two subsets of astrocytes in the spinal cord dorsal root entry zone (DREZ) following dorsal root lesion (Beggah et al… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

Inhibition of CNS remyelination by the presence of semaphorin 3A.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2011
View 1 Excerpt

Diverse functions of perineuronal nets.

Acta neurobiologiae experimentalis • 2009
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 39 references

Chondroitinase ABC promotes sprouting of intact and injured spinal systems after spinal cord injury.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2006
View 12 Excerpts
Highly Influenced

Regeneration failure in the CNs: cellular and molecular mechanisms.

Advances in experimental medicine and biology • 2006
View 1 Excerpt

Similar Papers

Loading similar papers…