Delayed parasite clearance after treatment with dihydroartemisinin-piperaquine in Plasmodium falciparum malaria patients in central Vietnam.

@article{Thriemer2014DelayedPC,
  title={Delayed parasite clearance after treatment with dihydroartemisinin-piperaquine in Plasmodium falciparum malaria patients in central Vietnam.},
  author={Kamala Thriemer and Nguyễn Văn Hồng and Anna Rosanas-Urgell and Bui Quang Phuc and Do Manh Ha and Evi Pockele and Pieter Guetens and Nguyen Van Van and Tran Thanh Duong and Alfred Amambua-Ngwa and Umberto D'Alessandro and Annette Erhart},
  journal={Antimicrobial agents and chemotherapy},
  year={2014},
  volume={58 12},
  pages={
          7049-55
        }
}
Reduced susceptibility of Plasmodium falciparum toward artemisinin derivatives has been reported from the Thai-Cambodian and Thai-Myanmar borders. Following increasing reports from central Vietnam of delayed parasite clearance after treatment with dihydroartemisinin-piperaquine (DHA-PPQ), the current first-line treatment, we carried out a study on the efficacy of this treatment. Between September 2012 and February 2013, we conducted a 42-day in vivo and in vitro efficacy study in Quang Nam… CONTINUE READING
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