Delayed onset of malaria--implications for chemoprophylaxis in travelers.

  title={Delayed onset of malaria--implications for chemoprophylaxis in travelers.},
  author={Elias Schwartz and Monica Parise and Phyllis E. Kozarsky and Martin S. Cetron},
  journal={The New England journal of medicine},
  volume={349 16},
BACKGROUND Most antimalarial agents used by travelers act on the parasite's blood stage and therefore do not prevent late-onset illness, particularly that due to species that cause relapsing malaria. We examined the magnitude of this problem among Israeli and American travelers. METHODS We examined malaria surveillance data from Israel and the United States to determine the traveler's destination, the infecting species, the type of chemoprophylaxis used, and the incubation period. RESULTS… CONTINUE READING